Serina Therapeutics reported its QQ1 2025 results with no material revenue and a continued burn driven by R&D and general & administrative expenses. Total operating expenses for the quarter were $5.858 million, comprised of $2.951 million in R&D and $2.907 million in G&A, yielding an EBITDA of -$4.805 million and an operating loss of -$5.858 million. Net income was -$4.813 million, or -$0.49 per share on 9.756 million weighted-average shares, reflecting ongoing pre-commercial development activity across the company’s pipeline. Cash burn from operating activities amounted to -$4.322 million during QQ1 2025, while financing activity provided a cash inflow of $4.917 million from common stock issuance, resulting in a modest net cash increase of $0.595 million and ending cash of $4.267 million.
The balance sheet shows a tight but improving liquidity position for a pre-revenue biotech: total assets of $6.731 million vs. total liabilities of $5.172 million, and stockholders’ equity of $1.701 million alongside a substantial accumulated deficit of $49.131 million. The company also reports net debt of approximately -$4.04 million, reflecting cash on hand exceeding debt obligations. Management commentary is not included in the provided transcript data, but the quarter’s performance aligns with the typical early-stage biotech profile: meaningful R&D investment, near-term cash burn, and a reliance on equity financing to fund pipeline activities.
From a medical and strategic perspective, Serina continues to advance a multi-product strategy focused on SER-252 (POZ conjugate for Parkinson’s disease) and SER-227 (long-acting pain relief), among other programs. While there is no revenue yet, the company’s trajectory will hinge on upcoming pipeline milestones, IND/clinical progression, and potential partnerships or licensing discussions that could convert scientific progress into value inflection points for investors.
Key Performance Indicators
Operating Income
Decreasing
-5.86M
QoQ: -5.57% | YoY: -152.39%
Net Income
Increasing
-4.81M
QoQ: -75.66% | YoY: 49.00%
EPS
Increasing
-0.49
QoQ: -58.06% | YoY: 85.50%
Revenue Trend
Margin Analysis
Financial Highlights
Revenue: $0 for QQ1 2025 (no revenue reported). YoY: N/A; QoQ: N/A.
Gross Profit: N/A.
Operating Income: -$5.858 million for QQ1 2025, with a YoY change of -152.39% and QoQ change of -5.57%.
Net Income: -$4.813 million, YoY +49.00% (improved vs prior periods despite losses) and QoQ -75.66%.
EPS: -$0.49 for QQ1 2025, YoY +85.50% and QoQ -58.06%.
R&D Expenses: $2.951 million.
G&A Expenses: $2.907 million.
Depreciation & Amortization: $0.017 million.
EBITDA: -$4.805 million.
Net Cash from Operating Activities: -$4.322 million.
Free Cash Flow: -$4.322 million.
Cash, Cash Equivalents: $4.267 million.
Total Liabilities: $5.172 million.
Total Stockholders’ Equity: $1.701 million.
Accumulated Deficit: -$49.131 million.
Net Debt: -$4.040 million (cash greater than debt).
Income Statement
Metric
Value
YoY Change
QoQ Change
Operating Income
-5.86M
-152.39%
-5.57%
Net Income
-4.81M
49.00%
-75.66%
EPS
-0.49
85.50%
-58.06%
Key Financial Ratios
Return on Assets
Weak
-0.72%
Return on assets suggests inefficient capital allocation
Return on Equity
Weak
-2.83%
Return on equity suggests inefficient capital allocation
Current Ratio
Healthy
2.45
Current ratio shows adequate liquidity to meet short-term obligations
Debt to Equity
Conservative
0.13
Debt-to-equity shows conservative leverage and low financial risk
P/E Ratio
Negative
-2.87x
Negative earnings make P/E ratio not meaningful
Price to Book
High Premium
32.52x
Very high premium suggests asset-light business model or lofty expectations
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