KalVista Pharmaceuticals Inc

KalVista Pharmaceuticals Inc a clinical stage pharmaceutical company discovers develops and commercializes small molecule protease inhibitors for diseases with unmet needs The companys product portfolio comprises small molecule plasma kallikrein inhibitors targeting hereditary angioedema HAE and diabetic macular edema DME and oral plasma kallikrein inhibitors Its products include KVD001 a plasma kallikrein inhibitor that completed a Phase II clinical trial for the treatment of DME sebetralstat which is initiation of the Phase 3 KONFIDENT trial as a potential oral ondemand therapy for HAE attacks KVD824 an oral product candidate for the treatment of HAE and Factor XIIa an oral inhibitor program which is in preclinical stage targets an enzyme in HAE The company is headquartered in Cambridge Massachusetts