Reported Q: Q1 2024 Rev YoY: +76.5% EPS YoY: +1,264.4% Move: +4.74%
CytomX Therapeutics Inc
CTMX
$4.42 4.74%
Exchange NASDAQ Sector Healthcare Industry Biotechnology
Q1 2024
Published: May 8, 2024

Company Status Snapshot

Fast view of the latest quarter outcome for CTMX

Reported

Report Date

May 8, 2024

Quarter Q1 2024

Revenue

41.46M

YoY: +76.5%

EPS

0.17

YoY: +1,264.4%

Market Move

+4.74%

Previous quarter: N/A

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Earnings Highlights

  • Revenue of $41.46M up 76.5% year-over-year
  • EPS of $0.17 increased by 1% from previous year
  • Gross margin of 100.0%
  • Net income of 13.79M
  • ""CX-904 has 1 CD3 binding domain and 1 EGFR binding domain. Both domains are masked with unique peptides. Furthermore, the protease cleanable substrates are different in each binding domain, reflecting our preclinical fine-tuning strategy for optimization of therapeutic window." - Quote attributed to Sean McCarthy, CytomX Chief Executive Officer and Chairman" - Sean McCarthy
CTMX
Company CTMX

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Executive Summary

CytomX Therapeutics reported a Q1 2024 QQ1 quarter characterized by a strong revenue base driven by collaboration activity and meaningful clinical progress for CX-904, its EGFR-CD3 Probody T-cell engager. Revenue of $41.46 million delivered a gross profit of $41.46 million with an EBITDA of $12.12 million and a net income of $13.79 million, aided by approximately $2.18 million of other income and favorable non-operating items. Management highlighted the Phase I CX-904 dose-escalation program, noting an encouraging safety profile with no CRS or ICANS across non-step dosing and step-dose cohorts, and early signs of antitumor activity in pancreatic cancer (including confirmed partial responses) and disease control in a broader set of EGFR-positive tumors. The company also underscored steady progress across the pipeline (CX-2051, CX-801) and ongoing collaboration milestones (e.g., $10 million in milestone payments from the Astellas bispecific collaboration). Net cash flow from operations was negative (-$26.0 million) driven largely by working capital movements, while cash on hand showed a balance of $36.2 million at period-end under the reported balance sheet, with citations in the call noting a cash runway into 2025 subject to collaborations and future milestones. This juxtaposition of a robust revenue base from partnerships with early-stage clinical momentum in CX-904 establishes CytomX as a collaboration-centric biotech with optionality across multiple Probody programs. Investors should monitor the Company’s ability to extend MXD-like cash runway via milestones, the evolution of RP2D for CX-904, and data readouts for its EpCAM and interferon assets in 2025–2026.

Key Performance Indicators

Revenue
Increasing
41.46M
QoQ: 55.83% | YoY: 76.45%
Gross Profit
Increasing
41.46M
1.00% margin
QoQ: 58.73% | YoY: 88.44%
Operating Income
Increasing
11.66M
QoQ: 2 023.60% | YoY: 306.21%
Net Income
Increasing
13.79M
QoQ: 1 547.67% | YoY: 1 523.22%
EPS
Increasing
0.17
QoQ: 1 270.97% | YoY: 1 264.38%

Revenue Trend

Margin Analysis

Historical Earnings Comparison

PeriodRevenue ($M)EPS ($)YoY GrowthReport
Q1 2025 50.92 0.27 +22.8% View
Q4 2024 38.09 0.22 +43.2% View
Q3 2024 33.43 0.07 +26.7% View
Q2 2024 25.12 -0.08 +1.6% View
Q1 2024 41.46 0.17 +76.5% View