Executive Summary
Abeona Therapeutics reported Q4 2024 revenue of $4.782 million, representing a 69.3% year-over-year increase from the prior-year Q4. The gross profit of $2.391 million yielded a gross margin of 50.0%, but the company posted an operating loss of $16.672 million and a net loss of $9.293 million for the quarter, with negative EBITDA of $7.435 million. Earnings per share were negative at $0.23 on 41.05 million weighted-average shares. The narrative highlights a classic biotech burn profile in a period of top-line growth, driven by ongoing R&D activity and pipeline development, rather than near-term commercialization visibility. Operating cash flow was negative at $16.559 million for the quarter, with free cash flow negative at $17.165 million, underscoring a continued cash burn despite a favorable gross margin on the modest revenue base.
On the balance sheet, Abeona holds substantial liquidity: cash and short-term investments totaled approximately $97.72 million, with cash at period end around $23.70 million. Total liabilities stood at about $64.9 million, and net debt was modestly negative at approximately $0.31 million, reflecting net cash on hand after debt. Retained earnings are deeply negative, driven by cumulative losses prior to this quarter, while total stockholders’ equity was about $44.0 million, signaling a fragile, early-stage profitability profile but a cushion from liquidity assets that may support ongoing development or financing activity. The current ratio is robust at 6.08, implying strong near-term liquidity, though cash burn and dependence on external funding remain key investment risks.
Looking forward, no formal quarterly or annual guidance is provided in the available data. Given Abeona’s lead EB101 program in recessive dystrophic epidermolysis bullosa (RDEB) in Phase III and several ABO programs in earlier stages, catalysts will likely hinge on trial progression, readouts, and potential strategic partnerships or financings to support operations and pipeline advancement. The investment thesis rests on successful clinical outcomes and the ability to secure additional funding to bridge to potential value inflection points.
Key Performance Indicators
QoQ: 431.16% | YoY:69.33%
QoQ: -8.65% | YoY:-26.22%
Key Insights
Revenue in Q4 2024: $4.782 million, up 69.3% YoY from Q4 2023. Gross profit: $2.391 million with a gross margin of 50.0% for the quarter; QoQ gross profit growth was significant due to the absence of revenue in the prior quarter (Q3 2024) and the incremental revenue in Q4. Operating expenses: $16.672 million (R&D $8.994 million; G&A $7.678 million); EBITDA: -$7.435 million; Operating income: -$16.672 million; Net income: -$9.293 million; EPS: -$0.23 on 41.048 million weighted-average sha...
Financial Highlights
Revenue in Q4 2024: $4.782 million, up 69.3% YoY from Q4 2023. Gross profit: $2.391 million with a gross margin of 50.0% for the quarter; QoQ gross profit growth was significant due to the absence of revenue in the prior quarter (Q3 2024) and the incremental revenue in Q4. Operating expenses: $16.672 million (R&D $8.994 million; G&A $7.678 million); EBITDA: -$7.435 million; Operating income: -$16.672 million; Net income: -$9.293 million; EPS: -$0.23 on 41.048 million weighted-average shares (diluted).
Cash flow and liquidity: Net cash used in operating activities: -$16.559 million; Free cash flow: -$17.165 million; Net cash used for investing activities: -$18.876 million; Net cash provided by financing activities: $5.314 million; Net change in cash: +$7.631 million; Cash at end of period: $23.695 million; Cash and short-term investments: $97.72 million total; Total current assets: $100.853 million; Total assets: $108.931 million; Total liabilities: $64.900 million; Long-term debt: $16.299 million; Short-term debt: $6.749 million; Net debt: -$0.309 million; Retained earnings: -$813.258 million; Total stockholders’ equity: $44.031 million.
Key valuation and efficiency indicators: Current ratio 6.08, quick ratio 6.08, debt-to-assets 0.212, debt-to-equity 0.523, price-to-book 5.79, price-to-earnings negative (loss-making). Operating cash flow per share: -$0.363; Free cash flow per share: -$0.376; Cash per share: $2.15. These metrics reflect a liquidity cushion but a high-duration burn profile typical of clinical-stage biotechs awaiting meaningful top-line milestones.
Income Statement
Metric |
Value |
YoY Change |
QoQ Change |
Revenue |
4.78M |
69.33% |
N/A |
Gross Profit |
2.39M |
69.33% |
431.16% |
Operating Income |
-16.67M |
-26.22% |
-8.65% |
Net Income |
-9.29M |
43.99% |
69.30% |
EPS |
-0.23 |
64.62% |
63.49% |
Key Financial Ratios
operatingCashFlowPerShare
$-0.36
freeCashFlowPerShare
$-0.38
Management Commentary
Note: No earnings call transcript data were provided in the input. As a result, there are no management quotes to extract or themes to analyze. If a transcript becomes available, I can integrate management commentary on program timelines, capital strategy, and potential partnerships into this section.
Forward Guidance
No explicit forward-looking guidance was disclosed in the provided data. Given Abeona’s clinical-stage profile and the scale of R&D investment required to advance EB101 (Phase III) and ABO programs, the company will likely rely on ongoing financing activities to support operations until program milestones materialize. Investors should monitor: (1) any updates on EB101 Phase III trial progress or readouts, (2) potential strategic partnerships or licensing discussions for late-stage or preclinical programs, and (3) capital-raising plans or debt facilities that could extend the liquidity runway. Absent new financing, the current quarterly cash burn suggests a limited standalone runway; catalysts that could alter this trajectory include compelling trial data, regulatory milestones, or a funding event.